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Cas No. |
Product name |
670220-88-9 |
Crenolanib (CP-868596) |
more... |
Crenolanib (CP-868596) is a potent and selective inhibitor of PDGFRα/β with Kd of 2.1 nM/3.2 nM, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, ... |
154447-35-5 |
NU7026 |
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NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR. |
952021-60-2 |
PF-477736 |
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PF-477736 is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~10... |
911222-45-2 |
LY2603618 |
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LY2603618 is a selective Chk1 inhibitor with potential anti-tumor activity. Phase 2. |
587841-73-4 |
ZCL278 |
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ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM. |
516480-79-8 |
BML277 |
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BML-277 (C 3742) is a selective Chk2 (checkpoint kinase 2) inhibitor with an IC50 of 15 nM. |
1469337-95-8 |
K-Ras(G12C) inhibitor 12 |
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K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). |
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